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West Indies defeated Bangladesh by 201 runs on Tuesday to win the first Test, wrapping up a quick victory when tailender Shoriful Isman was forced to retire hurt.
Chasing an unlikely 334 to win, and resuming on their overnight score of 109-7, Bangladesh lost Jaker Ali and Hasan Mahmud to fast bowler Alzarri Joseph early in the first session of the final day at North Sound.
With Bangladesh on 132-9, last-man Shoriful retired injured having been hit on the back of his shoulder ducking into a bouncer by Joseph in the fifth over of the day.
Joseph had already removed Mahmud in the third over of the morning with the batsman caught behind for nought.
Jaker's innings came to an end on 31 when he was lbw to Joseph.
Jaker, who made a half century in the first innings, was just one of four Bangladesh batsmen to reach double figures in the second innings with skipper Mehidy Hasan Miraz top-scoring with 45.
Opening bowlers Kemar Roach (3-20) and Jayden Seales (3-45) did the bulk of the damage for the home side.
The second Test of the series gets underway in Jamaica on Saturday.