Australia will host Bangladesh in Darwin and Mackay, with the opening Test marking their first Test against the Tigers on home soil since 2003.
Hazlewood, who missed the teams' previous Test series in 2017 and did not feature in Australia's white-ball tour of Bangladesh earlier this year, has faced Bangladesh only nine times in his 15-year international career.
Speaking on the Unplayable Podcast, Hazlewood said the lack of familiarity with both the opposition and the conditions makes the contest exciting.
"There's a lot of unknowns going in," Hazlewood said. "You've got the ground, that's an unknown. The wicket in particular, (and) the opposition in these conditions. So there are a lot of unknowns, but I think it's exciting."
The veteran quick said Australia would study Bangladesh's batters but expected to adjust their plans during the match if required.
"There's definitely footage and we can find some trends against these batters, but it might be a case of summing it up out there and coming up with plans on the run as well, which is always refreshing," he said.
The first Test between Australia and Bangladesh begins in Darwin on August 13.